Searchable abstracts of presentations at key conferences in endocrinology

ea0022gh1 | The Geoffrey Harris Prize Lecture | ECE2010

Transgenes and physiology in the Growth Hormone axis: a view from the portal

Robinson Iain

Neuroendocrine cascades regulate essential processes in integrative physiology, such as growth and metabolism, reproduction, and responses to stress. The pioneering work of Geoffrey Harris showed that the pituitary gland, the major endocrine regulator of these processes, is itself controlled by hypothalamic neurones that secrete their products into the hypophysial portal circulation. Intermingling of pituitary cell types and the complex anatomical distribution of the different...

ea0022gh1biog | The Geoffrey Harris Prize Lecture | ECE2010

Geoffrey Harris Prize Winner

Robinson Iain

Iain Robinson, UK AbstractThis prestigious prize is intended for established workers in field of basic and clinical neuroendocrinology, and is generously supported by Ipsen. This year's recipient is Professor Iain Robinson. The prize will be presented as part of the ECE 2010 opening ceremony where Professor Robinson will deliver his lecture. Professor robinson will also deliver two other lectures at fut...

ea0016s28.1 | GH: structure–function relationship | ECE2008

Plasticity in the growth hormone axis

Robinson Iain

Pituitary growth hormone (GH) is released in a highly pulsatile fashion in response to stimuli from its hypothalamic regulators, GH releasing hormone (GHRH) and somatostatin (SRIF), as well as feedback from peripheral signals. This interplay is complex, and still poorly understood. GHRH is a major factor in controlling pituitary GH synthesis and somatotroph cell number as well as GH secretion, and lack of GHRH or its receptor cause profound somatotroph hypoplasia and dwarfism....